Infusion Care Learning
Guide for healthcare professionals
Welcome to your go-to resource for using Neria™ infusion sets to support the
subcutaneous delivery of medications.*
Go through each section step-by-step, or navigate using the tabs
*Please refer to the instructions for use that come with the Neria™ infusion sets for intended use and indications.
The choice of medication and method of administration rely on the assessment of healthcare professionals.
Introduction
What is subcutaneous infusion and where is Neria™ indicated?
Subcutaneous infusion continuously delivers medication over a longer period - in the fatty tissue beneath the skin.
On this page: Indications FAQ's
What is subcutaneous infusion?
Subcutaneous infusion continuously delivers medication over a longer period into fatty tissue beneath the skin, where the body absorbs it. A needle penetrates the skin, leaving either the needle or a soft catheter in the tissue for up to 72 hours.
Needles and cannulas can vary in length, size, features and method of insertion. Using an infusion set for continuous subcutaneous infusion requires fewer injections (insertions) compared to injection therapy.
- Infusion pump
- Tubing
- Infusion set with needle and adhesive
The specific treatment set-up and type of medication is always determined by a healthcare professional.
Where is Neria indicated for use?
Palliative care
Pain management is an important part of end of life care for individuals with serious illnesses where the aim is to improve quality of life. (1)
Parkinsons
Parkinson’s disease is a movement disorder of the nervous system that worsens over time. Certain treatments can be administered subcutaneously to provide a steady level of medication in the body. (2)
Immunodeficiencies
Subcutaneous infusion can deliver immunoglobulin (antibodies) under the skin to treat immunodeficiencies, which refers to a group of either inherited (primary immunodeficiencies) or acquired disorders that prevent the body’s immune system from working properly. (3)
Thalassemia
A heterogeneous group of blood disorders that affect haemoglobin, thalassemia results in iron overload and can be treated using iron chelating drugs delivered subcutaneously. (4)
Common Questions Answered
Neria™ infusion sets are medical devices designed for subcutaneous drug delivery. The infusion set is located in the subcutaneous tissues and connects the pump or syringe to the body.
The components of an infusion set include:
- Needle and/or cannula – the cannula is inserted under the skin using an introducer needle
- Adhesive – built-in and adhesive pad
- Tubing - Double layer tubing designed to be strong, kink free and transparent (5)
- Luer lock connector – a standard connector to the syringe or pump
The Neria™ range of infusion sets come with either soft catheters or steel needles for the subcutaneous delivery of medications. The sets have been designed to be compatible with certain drugs approved for subcutaneous infusion for the treatment of Parkinson’s disease, primary Immunodeficiency, pain management, and thalassaemia.(5)
Stability testing has been carried out with the following drugs(5):
- Apomorphine and foslevodopa/foscarbidopa for Parkinson’s disease
- Immunoglobulins for Immune deficiencies
- Morphine and hydromorphone for pain management
- Desferal™ for thalassemia
What’s next?
1. NHS, Greater Manchester Health and Social Care Partnership. Palliative care pain and symptom control guidelines for adults. https://www.england.nhs.uk/north-west/wp-content/uploads/sites/48/2020/01/Palliative-<br>Care-Pain-and-Symptom-Control-Guidelines.pdf Accessed 13 August 2025 .
2. Kukkle PL, et al. Continuous Subcutaneous Infusion Delivery of Apomorphine in Parkinson&#39;s Disease: A Systematic Review. Mov Disord Clin Pract. 2023 Jun 26;10(9):1253-1267.
3. Immune deficiency foundation. https://primaryimmune.org/understanding-primary-immunodeficiency/treatment/immunoglobulin-replacement-therapy Accessed: 13 August 2025.
4. NHS, Imperial College Healthcare. Desferrioxamine (Desferal®): Information for patients, relatives and carers. https://www.imperial.nhs.uk/-/media/website/patient-information-leaflets/haematology/red-blood-cell-<br>disease/desferrioxamine.pdf?rev=1e57547aede64035abf00de0d04612f7&amp;sc_lang=en Accessed 13 August 2025.
5. Core Claims Table Convatec IC, data on file, D012-002912, 2023
Neria™
Get to know our infusion sets
A basic infusion set includes an insertion needle, adhesive pad, tubing and a luer-lock connector. The specific features of each Neria™ infusion set vary, and the right set will depend on your preferences and your patient’s treatment needs.
On this page: Components How to use Compare Real stories FAQ’s
Your choice for simplifying subcutaneous infusion
The Neria™ infusion sets are designed and approved for subcutaneous infusion in the treatment of diseases such as Parkinson’s disease, thalassemia, primary immune deficiency and pain management.*
*Convatec IC, data on file, D012-002912, 2023.
Neria™ infusion sets offer:
- Thin needles (G27)
- Built-in adhesive
- Double-layer, small bore tubing to minimise drug waste and priming volumes*
- Reduced risk of needle stick injury (with Neria™ Guard)*
- Tubing disconnect at the infusion site on Neria™ Guard and Neria™ Soft
- Standard luer-lock connection
Key components of an infusion set
All Neria™ infusion sets feature the same basic components. Neria™ Guard has an additional feature, which is a fully automatic insertion device.
Below you can read about all the components of an infusion set incl. the inserter.
Cannula housing
A plastic housing with a soft cannula or steel needle that is attached to the skin by an adhesive tape.
Soft cannula or steel needle
A small soft cannula or steel needle that is inserted into the subcutaneous skin layer and that allows the medication or fluid to flow into the body.
Tubing
A plastic tube that allows the medication or fluid to flow from the pump to the body.
Site connector
A connector that clicks into the cannula housing and connects the plastic tubing to the infusion set. It allows for temporary disconnection of the pump. (only for Neria™ Guard and Neria™ Soft)
Pump connector
A connecting lock that connects the plastic tubing to the infusion pump/syringe.
A single use insertion device/aid
Integrated with an automatic inserter needle. (reference: Core Claims Table Convatec IC, data on file, D012-002912, 2023)
Activation button
For automatic insertion (reference: Core Claims Table Convatec IC, data on file, D012-002912, 2023)
Safeguard
Safety tab helps minimise accidental activation (reference: Core Claims Table Convatec IC, data on file, D012-002912, 2023)
Double-layer tubing
Strong, kink resistant and helps minimise drug waste and priming volumes. (reference: Core Claims Table Convatec IC, data on file, D012-002912, 2023)
How to use
Step 1. Select and prepare the site
Step 1. Select and prepare the site
After washing your hands, clean the insertion site and leave to air dry. Note: You may need to remove hair from the a...
Read more Read moreStep 2: Prepare Neria™ Guard
After washing your hands, clean the insertion site and leave to air dry. Note: You may need to remove hair from the a...
Read more Read moreStep 3: Remove the safeguard
After washing your hands, clean the insertion site and leave to air dry. Note: You may need to remove hair from the a...
Read more Read moreStep 4: Insert the infusion set
Stretch the skin Please note that the following guide only illustrates some of the steps when inserting a Neria™ Guar...
Read more Read moreWatch the demonstration video
Follow this simple step-by-step guide when using the Neria™Guard automatic inserter.
Additional instructions for other Neria products Neria™ Soft infusion set
Comparing Neriaâ„¢ infusion sets
|
|
|
|
|
|
|
Cannula |
Soft |
Stainless Steel |
Soft |
Stainless Steel |
|
Insertion angle |
90 degrees |
90 degrees |
20-45 degrees |
90 degrees |
|
Disconnection feature |
Yes at site |
No |
Yes at site |
No |
|
Needle / Introducer needle gauge |
G27 |
G27 or G29 |
G27 |
G27 |
|
Needle lenghts |
6 or 9mm |
6, 8, 10 or 12mm |
13 or 17mm |
Bifurcated: 8, 10mm |
|
Tubbing lenghts |
12, 60, 110cm |
60, 110cm |
60, 110cm |
Total 90cm |
|
Adhesive |
Built-in |
Built-in |
Built-in |
Built-in |
|
Hidden needle |
Yes |
- |
- |
- |
|
Priming volumes |
12cm @ 0.04ml |
60cm @ 0.10ml |
60cm @ 0.10ml |
Bifurcated: 0.36ml |
From Health Care Professionals
“We create advanced solutions for the management of acute and chronic wounds resulting for ongoing conditions, such as diabetes, and acute conditions resulting from traumatic injuries and burns.”
David Shepherd
President and Chief Operating Officer, Advanced Wound Care
“We create advanced solutions for the management of acute and chronic wounds resulting for ongoing conditions, such as diabetes, and acute conditions resulting from traumatic injuries and burns.”
David Shepherd
President and Chief Operating Officer, Advanced Wound Care
Common Questions Answered
It is recommended that a Neria™ infusion set is changed after 72 hours for a soft catheter or 48 hours for a steel needle. Please consult the instructions for use that comes with the product for further information
No. The Neria™ infusion sets are specifically designed for subcutaneous drug delivery and are not intended for IV infusion of medication.
Neria™ Guard is an infusion set with an integrated needle safe and fully automatic inserter.
The user cannot see and is not exposed to the needle at any time, which can help protect the user from needle stick injuries.
Neria™ infusion sets have a standard luer lock connector and are compatible with most available infusion pumps.
The strong, double layer tubing included with Neria™ infusion sets is designed to be kink resistant. (Reference: Core Claims Table Convatec IC, data on file, D012-002912, 2023)
When disconnecting the tubing, you can use the caps to give a smoother surface at the site (cannula housing). The caps are included in the soft-catheter infusion sets (Neria™Guard and Neria™Soft).
What’s next?
Techniques
How to select and manage infusion sites
The following guidance can help you find the best places to insert an infusion set and how to rotate the insertion site to minimise any potential skin irritation.(1)(2)
On this page: Techniques Troubleshooting Test your knowledge FAQ’s
Site selection
Choosing the right placement
Typical insertion sites are on your lower back, abdomen, hips, buttocks, thigh or upper arm. Consider also cannula length when selecting the optimal insertion site for your patient.
Insertion tips:
- Make sure the site is clean and dry.
- Avoid sites in contact with constrictive clothing, such as a waistband, or other objects that can pull on the infusion set.
- Avoid the navel and surrounding area.
- Do not select a site that is infected, swollen, red, irritated, bruised or bleeding.
- Do not insert in an area with lumps, hard tissue or bumps.
- Do not insert into bone or muscle as this may cause pain, damage the product
and affect medication absorption.
Site rotation
Best practices and rotation patterns
It is important to not re-use the same insertion site.
- Use a pattern, such as a clock or snake, to guide the next insertion site placement.
- Choose a site that is at least 2.5 cm away from the previous site.*
- Leave the site to rest and do not re-use until the skin has healed.
Remember, the above rotation pattern is an example only. Consult local guidelines
and select the rotation pattern that works best for the individual patient.
*IEADSG Guidelines: Insulin Storage and Optimisation of Injection Technique in Diabetes Management, Diabetes Therapy, (2019) 10:341-366
Site management
Managing infusion over time
- Remember to visually inspect the infusion set and site several times each day.
- Follow recommended hygiene procedures and ensure the site remains clean and dry.
- Change the infusion set as per drug indication.
- Do not use any creams, oils or perfumes on the site.
- Gently massage the site after use.
- If nodules occur, consider ultrasound treatment. (Henriksen, Tove, and Harry Staines. “Continuous Subcutaneous Apomorphine Infusion in Parkinson's Disease: A Single- Center, Long-Term Follow-Up Study of the Causes for iscontinuation.” Journal of personalized medicine vol. 11,6 525. 8 Jun. 2021.)
Frequently asked questions
The most commonly used insertion sites for subcutaneous therapy are on the abdomen and lower back. Please read the product’s instructions for use and consider any local guidelines and protocols.
Some tips which may help reduce the risk of infusion site irritation include:
- Always clean and dry the insertion site prior to insertion.
- Massage the insertion site prior to insertion.
- Monitor the insertion site through the “window” of the soft catheter infusion set.
- Make sure to rotate the sites for instance by using a rotation pattern.
- Consider switching to a soft cannula infusion set and/or a shorter needle when faced with insertion site problems.
- If site irritation occurs, change the infusion set to a new site and massage the skin.
- Disclaimer: Please always refer to the instruction for use which comes with the product for further information and guidance.
Many factors can influence the condition of your skin. To help minimise skin complications, consider the following:
- Remember skin and hand hygiene prior to insertion.
- Use new areas for insertion, for instance the lower back and thighs.
- Use a rotation pattern to avoid re-using the same site.
- Avoid sites that already have site irritation or nodules.
- Use a site that does not interfere with clothing, belts etc.
- Massage the infusion site prior to insertion.
- Change the catheter material (from steel to soft), length or insertion technique.
- Disclaimer: Please always refer to the instruction for use which comes with the product for further information and guidance.
What’s next?
1. Hagell, Peter et al. “Apomorphine formulation may influence subcutaneous complications from continuous subcutaneous apomorphine infusion in Parkinson’s disease.” Journal of Neurology vol. 267,11 (2020): 3411-3417.
2. Fùˆrst, Per et al. “Continuous subcutaneous infusion for pain control in dying patients: experiences from a tertiary palliative care center.” BMC Palliative Care vol. 19,1 172. 10 Nov 2020.
Patient support
Equip your patients with knowledge and confidence
The following guidance can help you explain subcutaneous infusion to patients and answer their most common questions.
On this page: Everyday situations Common questions
Sports
Wearing an infusion set doesn’t have to hold your patients back, but it’s important to take precautions to avoid issu...
Learn more Learn moreShowering & bathing
Neria™Guard and Neria™Soft allow for disconnection of the tubing and pump, prior to taking a bath or shower.
Learn more Learn moreWork & daily life
When choosing an infusion set, consider the patient’s activity level. An infusion set with a disconnect option at sit...
Learn more Learn moreOn the go
When travelling, carry infusion sets in hand baggage in case of a delay and remember to carry spare sets.
Learn more Learn moreFrequently asked questions from patients
Yes, if using a soft catheter infusion set (Neria™Guard or Neria™Soft), the tubing and pump can be disconnected prior to a shower or bath. If the adhesive tape becomes loose, change to a new product and a new site. Check the insertion site frequently to ensure that the soft cannula or steel needle remain firmly in
place. If it is not in place, change to a new product and a new site.
Some tips which may reduce the risk of infusion site pain and irritation include:
- Always clean and dry the insertion site prior to insertion.
- Massage the insertion site prior to insertion.
- Monitor the insertion site through the “window” of the soft catheter infusion set.
Make sure to rotate the sites using one of the recommended patterns (for instance S-shape or clockwise). - Consider switching to a soft cannula infusion set and/or a shorter needle/soft catheter when faced with insertion site problems.
- If site irritation occurs, change the infusion set to a new site and massage the skin.
- Disclaimer: Please always refer to the instruction for use which comes with the product for futher information and guidance.
What’s next?
Knowledge Centre
Download Fact Cards
Fact Card One
PDF
Fact Card two
PDF
Fact Card Three
PDF
Instruction Videos
Video One
Video Two
Video 3
Further resources
Product range brochure
PDF
Site Management leaflet
PDF
Pain infographic
DOC
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